8.2
CiteScore
6.6
Impact Factor

2017 Vol. 44, No. 3

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Review
Metabolomics through the lens of precision cardiovascular medicine
Sin Man Lam, Yuan Wang, Bowen Li, Jie Du, Guanghou Shui
2017, 44(3): 127-138. doi: 10.1016/j.jgg.2017.02.004
Abstract (109) HTML PDF (1)
Abstract:
Metabolomics, which targets at the extensive characterization and quantitation of global metabolites from both endogenous and exogenous sources, has emerged as a novel technological avenue to advance the field of precision medicine principally driven by genomics-oriented approaches. In particular, m...
Original research
Using MutPred derived mtDNA load scores to evaluate mtDNA variation in hypertension and diabetes in a two-population cohort: The SABPA study
Marianne Venter, Leone Malan, Etresia van Dyk, Joanna L. Elson, Francois H. van der Westhuizen
2017, 44(3): 139-149. doi: 10.1016/j.jgg.2016.12.003
Abstract (82) HTML PDF (3)
Abstract:
Mitochondrial DNA (mtDNA) variation has been implicated in many common complex diseases, but inconsistent and contradicting results are common. Here we introduce a novel mutational load hypothesis, which also considers the collective effect of mainly rare variants, utilising the MutPred Program. We ...
Inscuteable maintains type I neuroblast lineage identity via Numb/Notch signaling in the Drosophila larval brain
Huanping An, Wanzhong Ge, Yongmei Xi, Xiaohang Yang
2017, 44(3): 151-162. doi: 10.1016/j.jgg.2017.02.005
Abstract (83) HTML PDF (2)
Abstract:
In the Drosophila larval brain, type I and type II neuroblasts (NBs) undergo a series of asymmetric divisions which give rise to distinct progeny lineages. The intermediate neural progenitors (INPs) exist only in type II NB lineages. In this study, we reveal a novel function of Inscuteable (Insc) th...
A cryptic mitochondrial DNA link between North European and West African dogs
Adeniyi C. Adeola, Sheila C. Ommeh, Jiao-Jiao Song, S. Charles Olaogun, Oscar J. Sanke, Ting-Ting Yin, Guo-Dong Wang, Shi-Fang Wu, Zhong-Yin Zhou, Jacqueline K. Lichoti, Bernard R. Agwanda, Philip M. Dawuda, Robert W. Murphy, Min-Sheng Peng, Ya-Ping Zhang
2017, 44(3): 163-170. doi: 10.1016/j.jgg.2016.10.008
Abstract (109) HTML PDF (4)
Abstract:
Domestic dogs have an ancient origin and a long history in Africa. Nevertheless, the timing and sources of their introduction into Africa remain enigmatic. Herein, we analyse variation in mitochondrial DNA (mtDNA) D-loop sequences from 345 Nigerian and 37 Kenyan village dogs plus 1530 published sequ...
Letter to the editor
Identification and analysis of intermediate-size noncoding RNAs in the rhesus macaque fetal brain
Liyuan Zhu, Xiaochao Tan, Wei Liu, Fengbiao Mao, Chao Wu, Junjie Zhou, Xiao Liu, Shuaiyao Lu, Kaili Ma, Bin Yin, Jianjun Luo, Jiangang Yuan, Boqin Qiang, Runsheng Chen, Xiaozhong Peng
2017, 44(3): 171-174. doi: 10.1016/j.jgg.2017.01.003
Abstract (75) HTML PDF (3)
Abstract:
High-efficiency breeding of early-maturing rice cultivars via CRISPR/Cas9-mediated genome editing
Xiufeng Li, Wenjia Zhou, Yuekun Ren, Xiaojie Tian, Tianxiao Lv, Zhenyu Wang, Jun Fang, Chengcai Chu, Jie Yang, Qingyun Bu
2017, 44(3): 175-178. doi: 10.1016/j.jgg.2017.02.001
Abstract (174) HTML PDF (17)
Abstract: