8.2
CiteScore
6.6
Impact Factor

2011 Vol. 38, No. 3

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Research article
Announcement
2011, 38(3): I-II. doi: 10.1016/S1673-8527(11)00046-4
Abstract (49) HTML PDF (0)
Abstract:
The impact of next-generation sequencing on genomics
Jun Zhang, Rod Chiodini, Ahmed Badr, Genfa Zhang
2011, 38(3): 95-109. doi: 10.1016/j.jgg.2011.02.003
Abstract (119) HTML PDF (1)
Abstract:
This article reviews basic concepts, general applications, and the potential impact of next-generation sequencing (NGS) technologies on genomics, with particular reference to currently available and possible future platforms and bioinformatics. NGS technologies have demonstrated the capacity to sequ...
HSP70 decreases receptor-dependent phosphorylation of Smad2 and blocks TGF-β-induced epithelial-mesenchymal transition
Yihao Li, Xianjiang Kang, Qiang Wang
2011, 38(3): 111-116. doi: 10.1016/j.jgg.2011.02.001
Abstract (91) HTML PDF (0)
Abstract:
Smad2 and Smad3, the intracellular mediators of transforming growth factor β (TGF-β) signaling, are directly phosphorylated by the activated type I receptor kinase, and then shuttle from the cytoplasm into the nucleus to regulate target gene expression. Here, we report that the 70-kDa heat-shock pro...
Mitochondrial DNA evidence supports northeast Indian origin of the aboriginal Andamanese in the Late Paleolithic
Hua-Wei Wang, Bikash Mitra, Tapas Kumar Chaudhuri, Malliya gounder Palanichamy, Qing-Peng Kong, Ya-Ping Zhang
2011, 38(3): 117-122. doi: 10.1016/j.jgg.2011.02.005
Abstract (178) HTML PDF (9)
Abstract:
In view of the geographically closest location to Andaman archipelago, Myanmar was suggested to be the origin place of aboriginal Andamanese. However, for lacking any genetic information from this region, which has prevented to resolve the dispute on whether the aboriginal Andamanese were originated...
A rice mutant displaying a heterochronically elongated internode carries a 100 kb deletion
Mika Hayashi-Tsugane, Masahiko Maekawa, Qian Qian, Hirokazu Kobayashi, Shigeru Iida, Kazuo Tsugane
2011, 38(3): 123-128. doi: 10.1016/j.jgg.2011.02.004
Abstract (183) HTML PDF (0)
Abstract:
We have isolated a recessive rice mutant, designated as indeterminate growth (ing), which displays creeping and apparent heterochronic phenotypes in the vegetative period with lanky and winding culms. Rough mapping and subsequent molecular characterization revealed that the ing mutant carries a larg...
Detection and identification of Vibrio parahaemolyticus by multiplex PCR and DNA–DNA hybridization on a microarray
Rongzhi Wang, Jiadong Huang, Wei Zhang, Guangmei Lin, Junwei Lian, Libin Jiang, Hongcong Lin, Songfa Wang, Shihua Wang
2011, 38(3): 129-135. doi: 10.1016/j.jgg.2011.02.002
Abstract (65) HTML PDF (0)
Abstract:
In this paper, we developed a rapid and accurate method for the detection of Vibrio parahaemolyticus strains, using multiplex PCR and DNA–DNA hybridization. Multiplex PCR was used to simultaneously amplify three diagnostic genes (tlh, tdh and fla) that serve as molecular markers of V. parahaemolytic...