Loss of lims1 causes aberrant cardiac remodeling and heart failure via activating gp130/Jak1/Stat3 pathway in zebrafish

doi: 10.1016/j.jgg.2025.04.003

• Wuming Qin ^a , 
• Xiaobo Yang ^a , 
• Lu Zhang ^b , 
• Linghui Cao ^c , 
• Shi Ouyang ^a , 
• Dafeng Yang ^d , 
• Yangzhao Zhou ^d , 
• Anji Chen ^e , 
• Tao Liao ^a , 
• Xinyu Zhu ^a , 
• Yuting Liu ^f , 
• Wei Tang ^a , 
• Tongtong Ma ^a , 
• Yiyue Tang ^a , 
• Yonghe Ding ^f     , 
• Yun Deng ^a    

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  a. Laboratory of Zebrafish Genetics, College of Life Sciences, Hunan Normal University, Changsha, Hunan 410081, China;

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  b. Department of Clinical Laboratory, Qingdao Women's and Children's Hospital, Qingdao, Shandong 266034, China;

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  c. The Affiliated Changsha Central Hospital, Hengyang Medical School, University of South China, Changsha, Hunan 410004, China;

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  d. Department of Cardiovascular Surgery, The Second Xiangya Hospital of Central South University, Changsha, Hunan 410011, China;

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  e. Hunan Provincial Key Laboratory of Regional Hereditary Birth Defects Prevention and Control, Changsha Hospital for Maternal & Child Health Care Affiliated to Hunan Normal University, Changsha, Hunan 410007, China;

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  f. The Affiliated Hospital of Qingdao University & Biomedical Sciences Institute, Qingdao Medical College of Qingdao University, Qingdao, Shandong 266021, China