Developmental systems biology flourishing on new technologies

Jing-Dong J. Han; Yi Liu; Huiling Xue; Kai Xia; Hong Yu; Shanshan Zhu; Zhang Chen; Wei Zhang; Zheng Huang; Chunyu Jin; Bo Xian; Jing Li; Lei Hou; Yixing Han; Chaoqun Niu; Timothy C. Alcon

doi:10.1016/S1673-8527(08)60078-8

Volume 35 Issue 10

Oct. 2008

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Article Navigation > Journal of Genetics and Genomics > 2008 > 35(10): 577-584

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Developmental systems biology flourishing on new technologies

doi: 10.1016/S1673-8527(08)60078-8

Jing-Dong J. Han^a,
Yi Liu^{a, b, #},
Huiling Xue^{a, #},
Kai Xia^{a, #},
Hong Yu^{a, #},
Shanshan Zhu^{a, #},
Zhang Chen^a,
Wei Zhang^a,
Zheng Huang^a,
Chunyu Jin^a,
Bo Xian^a,
Jing Li^a,
Lei Hou^a,
Yixing Han^a,
Chaoqun Niu^a,
Timothy C. Alcon^{a, c}

a
Chinese Academy of Sciences Key Laboratory of Molecular Developmental Biology, Center for Molecular Systems Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China
b
Key Laboratory of Machine Perception (Ministry of Education), Peking University, Beijing 100871, China
c
Bioinformatics and Computational Biology Graduate Program, Iowa State University, Ames, IA 50011-1040, USA

More Information

Corresponding author: E-mail address: jdhan@genetics.ac.cn (Jing-Dong J. Han)
Received Date: 2008-08-13
Accepted Date: 2008-09-05
Rev Recd Date: 2008-09-04

Available Online: 2008-10-18

Publish Date: 2008-10-20

Abstract

Abstract

Organism development is a systems level process. It has benefited greatly from the recent technological advances in the field of systems biology. DNA microarray, phenome, interactome and transcriptome mapping, the new generation of deep sequencing technologies, and faster and better computational and modeling approaches have opened new frontiers for both systems biologists and developmental biologists to reexamine the old developmental biology questions, such as pattern formation, and to tackle new problems, such as stem cell reprogramming. As showcased in the International Developmental Systems Biology Symposium organized by Chinese Academy of Sciences, developmental systems biology is flourishing in many perspectives, from the evolution of developmental systems, to the underlying genetic and molecular pathways and networks, to the genomic, epigenomic and noncoding levels, to the computational analysis and modeling. We believe that the field will continue to reap rewards into the future with these new approaches.
- developmental systems biology,
- new technologies,
- symposium

These authors contributed equally to this report.

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References(41)

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