The JNK Pathway and Neuronal Migration

Yiming Sun; Tao Yang; Zhiheng Xu

doi:10.1016/S1673-8527(07)60108-8

Volume 34 Issue 11

Nov. 2007

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Article Navigation > Journal of Genetics and Genomics > 2007 > 34(11): 957-965

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The JNK Pathway and Neuronal Migration

doi: 10.1016/S1673-8527(07)60108-8

Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China

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Corresponding author: E-mail address: zhxu@genetics.ac.cn (Zhiheng Xu)
Received Date: 2007-09-21
Accepted Date: 2007-09-27

Available Online: 2007-11-22

Publish Date: 2007-11-20

Abstract

Abstract

The c-Jun N-terminal kinases (JNKs) are important regulators of a variety of physiological and pathological processes both in the central and in the peripheral nervous systems. JNKs are considered as crucial mediators of neuronal cell death in response to stress and injury. However, recent studies have provided substantial evidence that the JNK pathway plays an important role in neuronal migration. Here, we will give a brief introduction of the JNK signaling pathway and put more emphasis on its role in neuronal migration.
- JNK pathway,
- neuronal migration,
- signal transduction

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References(68)

References

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