Detection of Quantitative Trait Loci Associated with Several Internal Organ Traits and Teat Number Trait in a Pig Population

Jinghu Zhang; Yuanzhu Xiong; Bo Zuo; Minggang Lei; Siwen Jiang; Feng'e Li; Rong Zheng; Jialian Li; Dequan Xu

doi:10.1016/S1673-8527(07)60032-0

Volume 34 Issue 4

Apr. 2007

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Article Navigation > Journal of Genetics and Genomics > 2007 > 34(4): 307-314

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Detection of Quantitative Trait Loci Associated with Several Internal Organ Traits and Teat Number Trait in a Pig Population

doi: 10.1016/S1673-8527(07)60032-0

a
Key Laboratory of Swine Genetics and Breeding, Ministry of Agriculture, College of Animal Science and Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China;
b
Department of Biology Science & Technology, Zhangzhou Normal College, Zhangzhou 363000, China

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Corresponding author: E-mail address: xiongyzh@public.wh.hb.cn (Yuanzhu Xiong)
Received Date: 2006-05-08
Accepted Date: 2006-05-19

Available Online: 2007-05-09

Publish Date: 2007-04-20

Abstract

Abstract

Quantitative trait loci (QTL) were detected for 8 internal organ traits, 3 carcass length traits, and teat number trait in 214 pigs in a resource population that included 180 F₂ individuals. A total of 39 microsatellite markers were examined on SSC4, SSC6, SSC7, SSC8, and SSC13. The genetic traits included heart weight (HW), lung weight (LW), liver and gallbladder weight (LGW), spleen weight (SPW), stomach weight (STW), small intestine weight (SIW), large intestine weight (LIW), kidney weight (KW), carcass length to the first cervical vertebra (CL1), carcass length to the first thoracic vertebra (CL2), rib numbers (RNS), and teat numbers (TNS). Results indicated that, 3 highly significant QTL (P ≤ 0.01 at chromosome-wise level) for HW (at 30 cM on SSC6), RNS (at 115 cM on SSC7), TNS (at 110 cM on SSC7), and 6 significant QTL (P ≤ 0.05 at chromosome-wise level) for LW (at 119 cM on SSC13), LGW (at 94 cM on SSC6), SPW (at 106 cM on SSC8), SIW (0 cM on SSC4), LIW (170 cM on SSC 4), and TNS (at 95 cM on SSC6) were detected. The phenotypic variances for which these QTL were accounted ranged from 0.04 % to 14.06 %. Most of these QTL had not been previously reported.
- pig,
- quantitative trait loci (QTL),
- internal organ weight traits,
- carcass length traits,
- teat number trait

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References(25)

References

[1]	Andersson, L, Haley, et al. Genetic mapping of quantitative trait loci for growth and fatness in pigs Science, 263 (1994),pp. 1771-1774
[2]	Andersson-Eklund, L, Marklund, et al. Mapping quantitative trait loci for carcass and meat traits in a Wild boar (Large White intercross Journal of Animal Science, 76 (1998),pp. 694-700
[3]	Bidanel, JP, Rothschild, et al. Current status of quantitative trait locus mapping in pigs Pig News and Information, 23 (2002),pp. 39N-54N
[4]	Su, YH, Xiong, et al. Detection of quantitative trait loci for growth in Large White (Meishan intercross Acta Genetica Sinica, 29 (2002),pp. 607-611
[5]	Su, YH, Xiong, et al. Mapping quantitative trait loci for fat deposition in carcass in pigs Acta Genetica Sinica, 29 (2002),pp. 681-684
[6]	Zuo, B, Xiong, et al. Mapping and genetic effect analysis of swine quantitative trait loci using 24 microsatellites Acta Veterinaria et Zootechnica Sinica (China), 34 (2003),pp. 139-146
[7]	Xiong, YZ, Deng, et al.
[8]	Zhang, JH, Xiong, et al. Genetic analysis and linkage mapping in a resource pig population by microsatellite markers Acta Genetica Sinica, 34 (2007),pp. 10-16
[9]	Green P, Falls K, Crooks S. Documentation for CRIMAP, Version 2.4. Washington University, school of Medicine, St. Louis, Mo, 1990.
[10]	Seaton, G, Haley, et al. QTL express: mapping quantitative trait loci in simple and complex pedigrees Bioinformatics Applications Note, 18 (2002),pp. 339-340
[11]	Haley, CS, Knott, et al. Mapping quantitative trait loci in crosses between outbred lines using least squares Genetics, 136 (1994),pp. 1195-1207
[12]	Ovilo, C, Perez-Enciso, et al. A QTL for intramuscular fat and backfat thickness is located on porcine chromosome 6 Mammalian Genome, 11 (2000),pp. 344-346
[13]	Churchill, GA, Doerge, et al. Empirical threshold values for quantitative trait mapping Genetics, 138 (1994),pp. 963-971
[14]	Su, YH, Xiong, et al. Construction of linkage map of chromosomes 1 and 3 in Large White × Meishan reference family Acta Genetica Sinica, 29 (2002),pp. 16-20
[15]	Zuo, B, Xiong, et al. Genetic linkage map construction of some microsatellites on pig chromosomes 4 and 7 Journal of Agricultural Biotechnology, 11 (2003),pp. 70-74
[16]	Lee, SS, Chen, et al. Linkage and QTL mapping for Sus scrofa chromosome 2 Journal of Animal Breeding and Genetics, 120 (2003),pp. 11-19
[17]	Beeckmann, P, Moser, et al. Linkage and QTL mapping for Sus scrofa chromosome 8 Journal of Animal Breeding and Genetics, 120 (2003),pp. 66-73
[18]	Geldermann, H, Muller, et al. Genome-wide linkage and QTL mapping in porcine F2 families generated from Pietrain, Meishan and Wild Boar crosses Journal of Animal Breeding and Genetics, 120 (2003),pp. 363-393
[19]	Dragos-Wendrich, M, Sternstein, et al. Linkage and QTL mapping for Sus scrofa chromosome 14 Journal of Animal Breeding and Genetics, 120 (2003),pp. 111-118
[20]	Cepica, S, Stratil, et al. Linkage and QTL mapping for Sus scrofa chromosome 4 Journal of Animal Breeding and Genetics, 120 (2003),pp. 28-37
[21]	Yue, G, Stratil, A, Cepica, S, , Schröffelova, D, Fontanesi, D, Cagnazzo, M, Moser, G., Bartenschlager, H, Reiner, G, Geldermann, H Linkage and QTL mapping for Sus scrofa chromosome 7 Journal of Animal Breeding and Genetics, 120 (2003),pp. 56-65
[22]	Yue, G, Stratil, et al. Linkage and QTL mapping for Sus scrofa chromosome 6 Journal of Animal Breeding and Genetics, 120 (2003),pp. 45-55
[23]	Cassady, JP, Johnson, et al. Identification of quantitative trait loci affecting reproduction in pigs Journal of Animal Science, 79 (2001),pp. 623-633
[24]	King, AH, Jiang, et al. Mapping quantitative trait loci affecting female reproductive traits on porcine chromosome 8 Biological Reproduction, 68 (2003),pp. 2172-2179
[25]	Wada, Y, Akita, et al. Quantitative trait loci (QTL) analysis in a Meishan x Gottingen crosspopulation Animal Genetics, 31 (2000),pp. 376-384