Abstract: Neural stem cells give rise to neurons through the process of neurogenesis, which includes neural stem cell proliferation, fate determination of new neurons, as well as the new neuron's migration, maturation and integration. Currently, neurogenesis is divided into two phases: embryonic and adult pha...
Abstract: Genetically modified animal models are important for understanding the pathogenesis of human disease and developing therapeutic strategies. Although genetically modified mice have been widely used to model human diseases, some of these mouse models do not replicate important disease symptoms or path...
Abstract: Balbiani body (BB) is a large distinctive organelle aggregate uniquely present in developing oocytes of diverse animal species. BB is thought as a stage-specific structure that resembles germ plasm, the cytoplasmic organelle of germ cells. The role and function of BB have remained speculative becaus...
Abstract: Previous studies have revealed the significance of cytokine interleukin 1 (IL-1) in the onset and progression of rheumatoid arthritis (RA). The precise molecular mechanisms related to IL-1 underlying RA is still elusive. We conducted a whole genome-wide transcriptomal comparison of wild-type (WT) an...
