9.9
CiteScore
7.1
Impact Factor

2008 Vol. 35, No. 7

Display Method:
Research article
A snapshot of the Chinese SOL Project
Changbao Li, Jiuhai Zhao, Hongling Jiang, Yu Geng, Yuanyuan Dai, Huajie Fan, Dongfen Zhang, Jinfeng Chen, Fei Lu, Jinfeng Shi, Shouhong Sun, Jianjun Chen, Xiaohua Yang, Chen Lu, Mingsheng Chen, Zhukuan Cheng, Hongqing Ling, Ying Wang, Yongbiao Xue, Chuanyou Li
2008, 35(7): 387-390. doi: 10.1016/S1673-8527(08)60056-9
Abstract (78) HTML PDF (0)
Abstract:
In 2003, the International Solanaceae Project (SOL) was initiated by an international consortium of ten countries including Korea, China, the United Kingdom, India, the Netherlands, France, Japan, Spain, Italy and the United States. The first major effort of the SOL aimed to produce a DNA sequence m...
Future impact of integrated high-throughput methylome analyses on human health and disease
Lee M Butcher, Stephan Beck
2008, 35(7): 391-401. doi: 10.1016/S1673-8527(08)60057-0
Abstract (85) HTML PDF (0)
Abstract:
A spate of high-powered genome-wide association studies (GWAS) have recently identified numerous single-nucleotide polymorphisms (SNPs) robustly linked with complex disease. Despite interrogating the majority of common human variation, these SNPs only account for a small proportion of the phenotypic...
Tackling the epigenome in the pluripotent stem cells
Xiaodong Zhao, Yijun Ruan, Chia-Lin Wei
2008, 35(7): 403-412. doi: 10.1016/S1673-8527(08)60058-2
Abstract (110) HTML PDF (2)
Abstract:
Embryonic stem cells are unique in their abilities of self-renewal and to differentiate into many, if not all, cellular lineages. Transcriptional regulation, epigenetic modifications and chromatin structures are the key modulators in controlling such pluripotency nature of embryonic stem cell genome...
Epigenetic regulation of genes during development: A conserved theme from flies to mammals
Dasari Vasanthi, Rakesh K Mishra
2008, 35(7): 413-429. doi: 10.1016/S1673-8527(08)60059-4
Abstract (73) HTML PDF (0)
Abstract:
Eukaryotic genome is organized in form of chromatin within the nucleus. This organization is important for compaction of DNA as well as for the proper expression of the genes. During early embryonic development, genomic packaging receives variety of signals to eventually set up cell type specific ex...
A stringent dual control system overseeing transcription and activity of the Cre recombinase for the liver-specific conditional gene knock-out mouse model
Yu Wu, Yinghua He, Hongyu Zhang, Xinlan Dai, Xiaoyu Zhou, Jun Gu, Guan Wang, Jingde Zhu
2008, 35(7): 431-439. doi: 10.1016/S1673-8527(08)60060-0
Abstract (103) HTML PDF (0)
Abstract:
Liver cancer is one of the most threatening diseases in Chinese population. Just like in other tissues, tumor initiation and development in liver involve multiple steps of genetic and epigenetic alterations with several unknown details. However, unlike in other tissues, a tissue specific inducible C...
Ectopic expression of soybean GmKNT1 in Arabidopsis results in altered leaf morphology and flower identity
Jun Liu, Da Ha, Zongming Xie, Chunmei Wang, Huiwen Wang, Wanke Zhang, Jinsong Zhang, Shouyi Chen
2008, 35(7): 441-449. doi: 10.1016/S1673-8527(08)60061-2
Abstract (91) HTML PDF (4)
Abstract:
Plant morphology is specified by leaves and flowers, and the shoot apical meristem (SAM) defines the architecture of plant leaves and flowers. Here, we reported the characterization of a soybean KNOX gene GmKNT1, which was highly homologous to Arabidopsis STM. The GmKNT1 was strongly expressed in ro...