3′ untranslated region somatic variants connect alternative polyadenylation dysregulation in human cancers

doi: 10.1016/j.jgg.2025.03.006

• Qiushi Xu ^a,b , 
• Xiaomeng Cheng ^a , 
• Qianru Li ^a , 
• Peng Yu ^a , 
• Xiaolan Zhou ^a , 
• Yu Chen ^a , 
• Limin Lin ^a , 
• Ting Ni ^a,c     , 
• Zhaozhao Zhao ^a,d    

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  a. State Key Laboratory of Genetic Engineering, National Clinical Research Center for Aging and Medicine, Huashan Hospital, Collaborative Innovation Center of Genetics and Development, Human Phenome Institute, Center for Evolutionary Biology, Shanghai Engineering Research Center of Industrial Microorganisms, School of Life Sciences, Fudan University, Shanghai 200438, China;

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  b. Center for Reproductive Medicine, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325027, China;

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  c. State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, Institutes of Biomedical Sciences, School of Life Sciences, Inner Mongolia University, Hohhot, Inner Mongolia 010070, China;

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  d. MOE Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai 200438, China