Eckenstaler, R., Hauke, M., Benndorf, R.A., 2022. A current overview of RhoA, RhoB, and RhoC functions in vascular biology and pathology. Biochem. Pharmacol. 206, 115321.
|
Elliott, L.T., Sharp, K., Alfaro-Almagro, F., Shi, S., Miller, K.L., Douaud, G., Marchini, J., Smith, S.M., 2018. Genome-wide association studies of brain imaging phenotypes in UK Biobank. Nature 562, 210-216.
|
Ferkingstad, E., Sulem, P., Atlason, B.A., Sveinbjornsson, G., Magnusson, M.I., Styrmisdottir, E.L., Gunnarsdottir, K., Helgason, A., Oddsson, A., Halldorsson, B.V., et al., 2021. Large-scale integration of the plasma proteome with genetics and disease. Nat. Genet. 53, 1712-1721.
|
Folkersen, L., Gustafsson, S., Wang, Q., Hansen, D.H., Hedman, A, K., Schork, A., Page, K., Zhernakova, D.V., Wu, Y., Peters, J., et al., 2020. Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals. Nat. Metab. 2, 1135-1148.
|
Grasby, K.L., Jahanshad, N., Painter, J.N., Colodro-Conde, L., Bralten, J., Hibar, D.P., Lind, P.A., Pizzagalli, F., Ching, C.R.K., McMahon, M.A.B., et al., 2020. The genetic architecture of the human cerebral cortex. Science 367.
|
Koprulu, M., Carrasco-Zanini, J., Wheeler, E., Lockhart, S., Kerrison, N.D., Wareham, N.J., Pietzner, M., Langenberg, C., 2023. Proteogenomic links to human metabolic diseases. Nat. Metab. 5, 516-528.
|
Mammucari, C., Milan, G., Romanello, V., Masiero, E., Rudolf, R., Del Piccolo, P., Burden, S.J., Di Lisi, R., Sandri, C., Zhao, J., et al., 2007. FoxO3 controls autophagy in skeletal muscle in vivo. Cell Metab. 6, 458-471.
|
McConaghy, J.R., McGuirk, R., 2019. Amblyopia: Detection and Treatment. Am. Fam. Physician. 100, 745-750.
|
Pietzner, M., Wheeler, E., Carrasco-Zanini, J., Cortes, A., Koprulu, M., Worheide, M.A., Oerton, E., Cook, J., Stewart, I.D., Kerrison, N.D., et al., 2021. Mapping the proteo-genomic convergence of human diseases. Science 374, eabj1541.
|
Pradhan, R., Yadav, S.K., Prem, N.N., Bhagel, V., Pathak, M., Shekhar, S., Gaikwad, S., Dwivedi, S.N., Bal, C.S., Dey, A.B., et al., 2020. Serum FOXO3A: a ray of hope for early diagnosis of Alzheimer's disease. Mech. Ageing Dev. 190, 111290.
|
Renault, V.M., Rafalski, V.A., Morgan, A.A., Salih, D.A., Brett, J.O., Webb, A.E., Villeda, S.A., Thekkat, P.U., Guillerey, C., Denko, N.C., et al., 2009. FoxO3 regulates neural stem cell homeostasis. Cell Stem Cell 5, 527-539.
|
Smith, S.M., Douaud, G., Chen, W., Hanayik, T., Alfaro-Almagro, F., Sharp, K., Elliott, L.T., 2021. An expanded set of genome-wide association studies of brain imaging phenotypes in UK Biobank. Nat. Neurosci. 24, 737-745.
|
Suhre, K., Arnold, M., Bhagwat, A.M., Cotton, R.J., Engelke, R., Raffler, J., Sarwath, H., Thareja, G., Wahl, A., DeLisle, R.K., et al., 2017. Connecting genetic risk to disease end points through the human blood plasma proteome. Nat. Commun. 8, 14357.
|
Sun, B., Maranville, J.C., Peters, J.E., Stacey, D., Butterworth, A.S., 2018. Genomic atlas of the human plasma proteome. Nature 558, 73-79.
|
Wang, Y., Lin, Y., Wang, L., Zhan, H., Luo, X., Zeng, Y., Wu, W., Zhang, X., Wang, F., 2020. TREM2 ameliorates neuroinflammatory response and cognitive impairment via PI3K/AKT/FoxO3a signaling pathway in Alzheimer's disease mice. Aging (Albany NY) 12, 20862-20879.
|
Yao, C., Chen, G., Song, C., Keefe, J., Mendelson, M., Huan, T., Sun, B.B., Laser, A., Maranville, J.C., Wu, H., et al., 2018. Genome-wide mapping of plasma protein QTLs identifies putatively causal genes and pathways for cardiovascular disease. Nat. Commun. 9, 3268.
|
Zhao, B., Li, T., Yang, Y., Wang, X., Luo, T., Shan, Y., Zhu, Z., Xiong, D., Hauberg, M.E., Bendl, J., et al., 2021. Common genetic variation influencing human white matter microstructure. Science 372, eabf3736.
|
Zhao, H., Rasheed, H., Noest, T.H., Cho, Y., Liu, Y., Bhatta, L., Bhattacharya, A., Hemani, G., Davey Smith, G., Brumpton, B.M., et al., 2022. Proteome-wide Mendelian randomization in global biobank meta-analysis reveals multi-ancestry drug targets for common diseases. Cell Genom. 2, None.
|
Zhao, J.H., Stacey, D., Eriksson, N., Macdonald-Dunlop, E., Hedman, A, K., Kalnapenkis, A., Enroth, S., Cozzetto, D., Digby-Bell, J., Marten, J., et al., 2023. Genetics of circulating inflammatory proteins identifies drivers of immune-mediated disease risk and therapeutic targets. Nat. Immunol. 24, 1540-1551.
|
Zheng, J., Haberland, V., Baird, D., Walker, V., Haycock, P.C., Hurle, M.R., Gutteridge, A., Erola, P., Liu, Y., Luo, S., et al., 2020. Phenome-wide Mendelian randomization mapping the influence of the plasma proteome on complex diseases. Nat. Genet. 52, 1122-1131.
|