ROS is essential for initiation of energy deprivation-induced autophagy

Choufei Wu; Yixing Li; Shu Zhong; Yingcong Chen; Yu Xie; Yuyao Feng; Weijing Yao; Suping Fu; Yanlan Zhu; Liefeng Wang; Yuting Chen; Liqin Zhang; Jingjing Tong; Cong Yi

doi:10.1016/j.jgg.2021.05.005

Volume 48 Issue 6

Jun. 2021

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Article Navigation > Journal of Genetics and Genomics > 2021 > 48(6): 512-515

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ROS is essential for initiation of energy deprivation-induced autophagy

doi: 10.1016/j.jgg.2021.05.005

a Key Laboratory of Vector Biology and Pathogen Control of Zhejiang Province, School of Life Sciences, Huzhou University, Huzhou 313000, China;
b Department of Biochemistry, and Department of Hepatobiliary and Pancreatic Surgery of the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310058, China;
c School of Life Sciences, Central China Normal University, Wuhan 430079, China;
d College of Chemistry and Bio-Engineering, Yichun University, Yichun 336000, China;
d Key Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases of Ministry of Education, Gannan Medical University, Ganzhou 341000, China

Funds:

We are grateful to Prof. Y. Ohsumi, Prof. H. Nakatogawa, and Prof. Zhiping Xie for the plasmids and yeast strains. We thank Prof. Yixian Cui, Prof. Zhi Hong, and other members of lab for constructive reading and discussing the manuscript and Dr. Chen Sun for ROS production analysis. The research was supported by the National Natural Science Foundation of China (32070739, 31771528, and 91754107), Zhejiang Provincial Natural Science Foundation of China (LR21C070001) and the National Basic Research Program of China (2017YFA0503402) to C. Yi, and Natural Science Foundation for Young Scientists of China (81800085), Natural Science Foundation of Hubei Province, China (ZRMS2020002147) to J. Tong, and Zhejiang Key R&D Program of China (2019C02030) to L. Zhang.

Received Date: 2021-03-16
Publish Date: 2021-06-20

Abstract

These authors contributed equally to this work.ology of the Second Affiliated

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