5.9
CiteScore
5.9
Impact Factor
Volume 48 Issue 5
May  2021
Turn off MathJax
Article Contents

Transcriptomic profiling of tumor microenvironment reveals distinct immune subgroups of metastatic melanoma and its potential implications for immunotherapy

doi: 10.1016/j.jgg.2021.03.008
  • Received Date: 2020-11-09
  • Publish Date: 2021-05-20
  • loading
  • Aran, D., Hu, Z., Butte, A.J., 2017. xCell:digitally portraying the tissue cellular heterogeneity landscape. Genome Biol. 18, 220.
    Becht, E., Giraldo, N.A., Lacroix, L., Buttard, B., Elarouci, N., Petitprez, F., Selves, J., Laurent-Puig, P., Sautès-Fridman, C., Fridman, W.H., et al., 2016. Estimating the population abundance of tissue-infiltrating immune and stromal cell populations using gene expression. Genome Biol. 17, 218.
    Chen, Y.-P., Wang, Y.-Q., Lv, J.-W., Li, Y.-Q., Chua, M.L.K., Le, Q.-T., Lee, N., Colevas, A.D., Seiwert, T., Hayes, D.N., et al., 2019. Identification and validation of novel microenvironment-based immune molecular subgroups of head and neck squamous cell carcinoma:implications for immunotherapy. Ann. Oncol. 30, 68-75.
    Edwards, J., Wilmott, J.S., Madore, J., Gide, T.N., Quek, C., Tasker, A., Ferguson, A., Chen, J., Hewavisenti, R., Hersey, P., et al., 2018. CD103+ tumor-resident CD8+ T cells are associated with improved survival in immunotherapy-naïve melanoma patients and expand significantly during anti-PD-1 treatment. Clin. Canc. Res. 24, 3036-3045.
    Johnson, D.B., Sosman, J.A., 2015. Therapeutic advances and treatment options in metastatic melanoma. JAMA Oncol. 1, 380-386.
    Li, T., Fan, J., Wang, B., Traugh, N., Chen, Q., Liu, J.S., Li, B., Liu, X.S., 2017. TIMER:a web server for comprehensive analysis of tumor-infiltrating immune cells. Canc. Res. 77, e108ee110.
    Luke, J.J., Flaherty, K.T., Ribas, A., Long, G.V., 2017. Targeted agents and immunotherapies:optimizing outcomes in melanoma. Nat. Rev. Clin. Oncol. 14, 463-482.
    Li, H., van der Leun, A.M., Yofe, I., Lubling, Y., Gelbard-Solodkin, D., van Akkooi, A.C.J., van den Braber, M., Rozeman, E.A., Haanen, J.B.A.G., Blank, C.U., et al., 2019. Dysfunctional CD8 T cells form a proliferative, dynamically regulated compartment within human melanoma. Cell 176, 775-789. e18.
    Newman, A.M., Liu, C.L., Green, M.R., Gentles, A.J., Feng, W., Xu, Y., Hoang, C.D., Diehn, M., Alizadeh, A.A., 2015. Robust enumeration of cell subsets from tissue expression profiles. Nat. Methods 12, 453-457.
    O'Donnell, J.S., Teng, M.W.L., Smyth, M.J., 2019. Cancer immunoediting and resistance to T cell-based immunotherapy. Nat. Rev. Clin. Oncol. 16, 151-167.
    Sade-Feldman, M., Yizhak, K., Bjorgaard, S.L., Ray, J.P., de Boer, C.G., Jenkins, R.W., Lieb, D.J., Chen, J.H., Frederick, D.T., et al., 2018. Defining T cell states associated with response to checkpoint immunotherapy in melanoma. Cell 175, 998-1013. e20.
    Sharma, P., Hu-Lieskovan, S., Wargo, J.A., Ribas, A., 2017. Primary, adaptive, and acquired resistance to cancer immunotherapy. Cell 168, 707-723.
    Sia, D., Jiao, Y., Martinez-Quetglas, I., Kuchuk, O., Villacorta-Martin, C., Castro de Moura, M., Putra, J., Camprecios, G., Bassaganyas, L., Akers, N., et al., 2017. Identification of an immune-specific class of hepatocellular carcinoma, based on molecular features. Gastroenterology 153, 812-826.
    Tirosh, I., Izar, B., Prakadan, S.M., Wadsworth, M.H. 2nd, Treacy, D., Trombetta, J.J., Rotem, A., Rodman, C., Lian, C., Murphy, G., et al., 2016. Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq. Science 352, 189-196.
    Van Allen, E.M., Miao, D., Schilling, B., Shukla, S.A., Blank, C., Zimmer, L., Sucker, A., Hillen, U., Foppen, M.H.G., Goldinger, S.M., et al., 2015. Genomic correlates of response to CTLA-4 blockade in metastatic melanoma. Science 350, 207-211.
    Yan, Y., Leontovich, A.A., Gerdes, M.J., Desai, K., Dong, J., Sood, A., SantamariaPang, A., Mansfield, A.S., Chadwick, C., Zhang, R., et al., 2019. Understanding heterogeneous tumor microenvironment in metastatic melanoma. PLoS One 14, e0216485.
    Zhang, Y., Kurupati, R., Liu, L., Zhou, X.Y., Zhang, G., Hudaihed, A., Filisio, F., GilesDavis, W., Xu, X., Karakousis, G.C., et al., 2017. Enhancing CD8+ T cell fatty acid catabolism within a metabolically challenging tumor microenvironment increases the efficacy of melanoma immunotherapy. Canc. Cell 32, 377-391. e9.
    Zhang, P., Xiong, X., Rolfo, C., Du, X., Zhang, Y., Yang, H., Russo, A., Devenport, M., Zhou, P., Liu, Y., et al., 2020. Mechanism-and immune landscape-based ranking of therapeutic responsiveness of 22 major human cancers to next generation antiCTLA-4 antibodies. Cancers 12, 284.
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Article Metrics

    Article views (166) PDF downloads (17) Cited by ()
    Proportional views
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return