Adrb1 and Adrb2b are the major β-adrenergic receptors regulating body axis straightening in zebrafish

Xiaoyu Wang; Shuo Wang; Zhaojun Meng; Chengtian Zhao

doi:10.1016/j.jgg.2020.10.009

Volume 47 Issue 12

Dec. 2020

Turn off MathJax

Article Contents

Article Navigation > Journal of Genetics and Genomics > 2020 > 47(12): 781-784

PDF( 1171 KB)

Adrb1 and Adrb2b are the major β-adrenergic receptors regulating body axis straightening in zebrafish

doi: 10.1016/j.jgg.2020.10.009

Xiaoyu Wang^{1, 2, 1},
Shuo Wang^{1, 2, 1},
Zhaojun Meng^{1, 2},
Chengtian Zhao^{3, 4, 5}

1
Institute of Evolution & Marine Biodiversity, Ocean University of China, Qingdao 266003, China
2
Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, Qingdao 266003, China
3
Institute of Evolution & Marine Biodiversity, Ocean University of China, Qingdao 266003, China
4
Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, Qingdao 266003, China
5
Ministry of Education Key Laboratory of Marine Genetics and Breeding, College of Marine Life Sciences, Ocean University of China, Qingdao 266003, China

More Information

Corresponding author: E-mail address: chengtian_zhao@ouc.edu.cn (Chengtian Zhao)
Publish Date: 2020-12-25

Abstract

These authors contributed equally to this work.

FullText(HTML)

References(20)

References

[1]	Banizs, B., Pike, M.M., Millican, C.L., Ferguson, W.B., Komlosi, P., Sheetz, J., Bell, P.D., Schwiebert, E.M., Yoder, B.K., 2005. Dysfunctional cilia lead to altered ependyma and choroid plexus function, and result in the formation of hydrocephalus. Development 132, 5329-5339.
[2]	Boswell, C.W., Ciruna, B., 2017. Understanding idiopathic scoliosis: a new zebrafish school of thought. Trends Genet. 33, 183-196.
[3]	Cheng, J.C., Castelein, R.M., Chu, W.C., Danielsson, A.J., Dobbs, M.B., Grivas, T.B., Gurnett, C.A., Luk, K.D., Moreau, A., Newton, P.O., Stokes, I.A., Weinstein, S.L., Burwell, R.G., 2015. Adolescent idiopathic scoliosis. Nat. Rev. Dis. Primers 1, 15030.
[4]	Grimes, D.T., Boswell, C.W., Morante, N.F., Henkelman, R.M., Burdine, R.D., Ciruna, B., 2016. Zebrafish models of idiopathic scoliosis link cerebrospinal fluid flow defects to spine curvature. Science 352, 1341-1344.
[5]	Ibanez-Tallon, I., Pagenstecher, A., Fliegauf, M., Olbrich, H., Kispert, A., Ketelsen, U.P., North, A., Heintz, N., Omran, H., 2004. Dysfunction of axonemal dynein heavy chain Mdnah5 inhibits ependymal flow and reveals a novel mechanism for hydrocephalus formation. Hum. Mol. Genet. 13, 2133-2141.
[6]	Myers, D.C., Sepich, D.S., Solnica-Krezel, L., 2002. Convergence and extension in vertebrate gastrulae: cell movements according to or in search of identity? Trends Genet. 18, 447-455.
[7]	Narita, K., Takeda, S., 2015. Cilia in the choroid plexus: their roles in hydrocephalus and beyond. Front. Cell Neurosci. 9, 39.
[8]	Oreskovic, D., Rados, M., Klarica, M., 2017. Role of choroid plexus in cerebrospinal fluid hydrodynamics. Neuroscience 354, 69-87.
[9]	Pierce, K.L., Premont, R.T., Lefkowitz, R.J., 2002. Seven-transmembrane receptors. Nat. Rev. Mol. Cell Biol. 3, 639-650.
[10]	Sassone-Corsi, P., 2012. The cyclic AMP pathway. Cold Spring Harb. Perspect. Biol. 4, a011148.
[11]	Singla, V., Reiter, J.F., 2006. The primary cilium as the cell's antenna: signaling at a sensory organelle. Science 313, 629-633.
[12]	Song, Z., Zhang, X., Jia, S., Yelick, P.C., Zhao, C., 2016. Zebrafish as a Model for Human Ciliopathies. J. Genet. Genomics 43, 107-120.
[13]	Spassky, N., Meunier, A., 2017. The development and functions of multiciliated epithelia. Nat. Rev. Mol. Cell. Biol. 18, 423-436.
[14]	Sternberg, J.R., Prendergast, A.E., Brosse, L., Cantaut-Belarif, Y., Thouvenin, O., Orts-Del'Immagine, A., Castillo, L., Djenoune, L., Kurisu, S., McDearmid, J.R., Bardet, P.L., Boccara, C., Okamoto, H., Delmas, P., Wyart, C., 2018. Pkd2l1 is required for mechanoception in cerebrospinal fluid-contacting neurons and maintenance of spine curvature. Nat. Commun. 9, 3804.
[15]	Tada, M., Heisenberg, C.P., 2012. Convergent extension: using collective cell migration and cell intercalation to shape embryos. Development 139, 3897-3904.
[16]	Thouvenin, O., Keiser, L., Cantaut-Belarif, Y., Carbo-Tano, M., Verweij, F., Jurisch-Yaksi, N., Bardet, P.L., van Niel, G., Gallaire, F., Wyart, C., 2020. Origin and role of the cerebrospinal fluid bidirectional flow in the central canal. eLife 9, e47699
[17]	Wallmeier, J., Frank, D., Shoemark, A., Nothe-Menchen, T., Cindric, S., Olbrich, H., Loges, N.T., Aprea, I., Dougherty, G.W., Pennekamp, P., Kaiser, T., Mitchison, H.M., Hogg, C., Carr, S.B., Zariwala, M.A., Ferkol, T., Leigh, M.W., Davis, S.D., Atkinson, J., Dutcher, S.K., 2019. De novo mutations in FOXJ1 result in a motile ciliopathy with hydrocephalus and randomization of left/right body asymmetry. Am. J. Hum. Genet. 105, 1030-1039.
[18]	Wang, Z., Nishimura, Y., Shimada, Y., Umemoto,. N, Hirano, M., Zang, L., Oka, T., Sakamoto, C., Kuroyanagi, J., Tanaka, T., 2009. Zebrafish beta-adrenergic receptor mRNA expression and control of pigmentation. Gene 446, 18-27.
[19]	Zhang, X., Jia, S., Chen, Z., Chong, Y.L., Xie, H., Feng, D., Wu, X., Song, D.Z., Roy, S., Zhao, C., 2018. Cilia-driven cerebrospinal fluid flow directs expression of urotensin neuropeptides to straighten the vertebrate body axis. Nat. Genet. 50, 1666-1673.
[20]	Zhao, C., Malicki, J., 2007. Genetic defects of pronephric cilia in zebrafish. Mech. Dev. 124, 605-616.