Rapid and efficient wounding for in vivo studies of neuronal dendrite regeneration and degeneration

Jianzhi Zhao; Xiaojie Wang; Xinan Meng; Wei Zou; Suhong Xu

doi:10.1016/j.jgg.2020.10.003

Volume 48 Issue 2

Feb. 2021

Turn off MathJax

Article Contents

Article Navigation > Journal of Genetics and Genomics > 2021 > 48(2): 163-166

PDF( 916 KB)

Rapid and efficient wounding for in vivo studies of neuronal dendrite regeneration and degeneration

doi: 10.1016/j.jgg.2020.10.003

Jianzhi Zhao^{1, #},
Xiaojie Wang^{2, 3, #},
Xinan Meng⁴,
Wei Zou^{5, 6},
Suhong Xu⁷

1
Center for Stem Cell and Regenerative Medicine and Department of Cardiology of the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310058 China
2
The Fourth Affiliated Hospital, Zhejiang University School of Medicine, Yiwu 322000, China
3
Institute of Translational Medicine, Zhejiang University, Hangzhou 310058, China
4
Center for Stem Cell and Regenerative Medicine and Department of Cardiology of the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310058 China
5
The Fourth Affiliated Hospital, Zhejiang University School of Medicine, Yiwu 322000, China
6
Institute of Translational Medicine, Zhejiang University, Hangzhou 310058, China
7
Center for Stem Cell and Regenerative Medicine and Department of Cardiology of the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310058 China

More Information

Corresponding author: E-mail address: zouwei@zju.edu.cn (Wei Zou); E-mail address: shxu@zju.edu.cn (Suhong Xu)
Received Date: 2020-07-28
Accepted Date: 2020-10-17
Rev Recd Date: 2020-09-24

Available Online: 2020-11-07

Publish Date: 2021-02-20

Abstract

These authors contributed equally to this work.

FullText(HTML)

References(19)

References

[1]	Byrne, A. B., Hammarlund, M., 2017. Axon regeneration in C. elegans: Worming our way to mechanisms of axon regeneration. Exp Neurol. 287, 300-309.
[2]	Cai, Q., Sheng, Z. H., 2009. Moving or stopping mitochondria: Miro as a traffic cop by sensing calcium. Neuron. 61, 493-496.
[3]	Chen, L., Wang, Z., Ghosh-Roy, A., Hubert, T., Yan, D., O’Rourke, S., Bowerman, B., Wu, Z., Jin, Y., Chisholm, A. D., 2011. Axon regeneration pathways identified by systematic genetic screening in C. elegans. Neuron. 71, 1043-1057.
[4]	Chisholm, A. D., Hutter, H., Jin, Y., Wadsworth, W. G., 2016. The Genetics of Axon Guidance and Axon Regeneration in Caenorhabditis elegans. Genetics. 204, 849-882.
[5]	E, L., Zhou, T., Koh, S., Chuang, M., Sharma, R., Pujol, N., Chisholm, A. D., Eroglu, C., Matsunami, H., Yan, D., 2018. An Antimicrobial Peptide and Its Neuronal Receptor Regulate Dendrite Degeneration in Aging and Infection. Neuron. 97, 125-138 e5.
[6]	Ghosh-Roy, A., Wu, Z., Goncharov, A., Jin, Y., Chisholm, A. D., 2010. Calcium and cyclic AMP promote axonal regeneration in Caenorhabditis elegans and require DLK-1 kinase. J Neurosci. 30, 3175-3183.
[7]	Inberg, S., Meledin, A., Kravtsov, V., Iosilevskii, Y., Oren-Suissa, M., Podbilewicz, B., 2019. Lessons from Worm Dendritic Patterning. Annu Rev Neurosci. 42, 365-383.
[8]	Jan, Y. N., Jan, L. Y., 2003. The control of dendrite development. Neuron. 40, 229-242.
[9]	Kim, K. W., Tang, N. H., Piggott, C. A., Andrusiak, M. G., Park, S., Zhu, M., Kurup, N., Cherra, S. J., 3rd, Wu, Z., Chisholm, A. D., Jin, Y., 2018. Expanded genetic screening in Caenorhabditis elegans identifies new regulators and an inhibitory role for NAD(+) in axon regeneration. Elife. 7, e39756.
[10]	Liu, H. H., Jan, Y. N., 2020. Mechanisms of neurite repair. Curr Opin Neurobiol. 63, 53-58.
[11]	Lopez-Domenech, G., Higgs, N. F., Vaccaro, V., Ros, H., Arancibia-Carcamo, I. L., MacAskill, A. F., Kittler, J. T., 2016. Loss of Dendritic Complexity Precedes Neurodegeneration in a Mouse Model with Disrupted Mitochondrial Distribution in Mature Dendrites. Cell Reports. 17, 317-327.
[12]	Mattson, M. P., Magnus, T., 2006. Ageing and neuronal vulnerability. Nat Rev Neurosci. 7, 278-294.
[13]	Nawabi, H., Zukor, K., He, Z., 2012. No simpler than mammals: axon and dendrite regeneration in Drosophila. Genes Dev. 26, 1509-1514.
[14]	Nix, P., Hammarlund, M., Hauth, L., Lachnit, M., Jorgensen, E. M., Bastiani, M., 2014. Axon regeneration genes identified by RNAi screening in C. elegans. J Neurosci. 34, 629-645.
[15]	Oren-Suissa, M., Gattegno, T., Kravtsov, V., Podbilewicz, B., 2017. Extrinsic Repair of Injured Dendrites as a Paradigm for Regeneration by Fusion in Caenorhabditis elegans. Genetics. 206, 215-230.
[16]	Verma, M., Callio, J., Otero, P. A., Sekler, I., Wills, Z. P., Chu, C. T., 2017. Mitochondrial Calcium Dysregulation Contributes to Dendrite Degeneration Mediated by PD/LBD-Associated LRRK2 Mutants. J Neurosci. 37, 11151-11165.
[17]	Xu, S., Chisholm, A. D., 2011. A Galphaq-Ca(2)(+) signaling pathway promotes actin-mediated epidermal wound closure in C. elegans. Curr Biol. 21, 1960-1967.
[18]	Xu, S., Chisholm, A. D., 2014. Methods for skin wounding and assays for wound responses in C. elegans. J Vis Exp. 94, e51959.
[19]	Zou, W., Shen, A., Dong, X., Tugizova, M., Xiang, Y. K., Shen, K., 2016. A multi-protein receptor-ligand complex underlies combinatorial dendrite guidance choices in C. elegans. Elife. 5, e18345.