Evolutionary selection on MDA5 and LGP2 in the chicken preserves antiviral competence in the absence of RIG-I

Ling Xu; Dandan Yu; Yu Fan; Yi-Ping Liu; Yong-Gang Yao

doi:10.1016/j.jgg.2019.10.001

Volume 46 Issue 10

Oct. 2019

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Article Navigation > Journal of Genetics and Genomics > 2019 > 46(10): 499-503

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Evolutionary selection on MDA5 and LGP2 in the chicken preserves antiviral competence in the absence of RIG-I

doi: 10.1016/j.jgg.2019.10.001

Ling Xu^{1, 2},
Dandan Yu^{3, 4},
Yu Fan^{5, 6},
Yi-Ping Liu⁷,
Yong-Gang Yao^{8, 9, 10, 11}

1
Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences & Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, 650223, China
2
Center for Excellence in Animal Evolution and Genetics, Chinese Academy of Sciences, Kunming, Yunnan, 650223, China
3
Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences & Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, 650223, China
4
Center for Excellence in Animal Evolution and Genetics, Chinese Academy of Sciences, Kunming, Yunnan, 650223, China
5
Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences & Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, 650223, China
6
Center for Excellence in Animal Evolution and Genetics, Chinese Academy of Sciences, Kunming, Yunnan, 650223, China
7
Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, Sichuan Agricultural University, Chengdu, Sichuan, 611130, China
8
Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences & Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, 650223, China
9
Center for Excellence in Animal Evolution and Genetics, Chinese Academy of Sciences, Kunming, Yunnan, 650223, China
10
Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming, Yunnan, 650204, China
11
KIZ – CUHK Joint Laboratory of Bioresources and Molecular Research in Common Diseases, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, 650223, China

More Information

Corresponding author: E-mail address: yaoyg@mail.kiz.ac.cn (Yong-Gang Yao)
Received Date: 2019-08-22
Accepted Date: 2019-10-19
Rev Recd Date: 2019-10-02

Available Online: 2019-11-05

Publish Date: 2019-10-20

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References(33)

References

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