Identifying normal embryos from reciprocal translocation carriers by whole chromosome haplotyping

Zhiqiang Yan; Yuqian Wang; Yanli Nie; Xu Zhi; Xiaohui Zhu; Meng Qin; Shuo Guan; Yixin Ren; Ying Kuo; Di Chang; Wei Chen; Peng Yuan; Liying Yan; Jie Qiao

doi:10.1016/j.jgg.2018.05.006

Volume 45 Issue 9

Sep. 2018

Turn off MathJax

Article Contents

Article Navigation > Journal of Genetics and Genomics > 2018 > 45(9): 505-508

PDF( 1077 KB)

Identifying normal embryos from reciprocal translocation carriers by whole chromosome haplotyping

doi: 10.1016/j.jgg.2018.05.006

Zhiqiang Yan^{a, b, c, d},
Yuqian Wang^{a, b, e},
Yanli Nie^{a, b, e},
Xu Zhi^{a, b, e},
Xiaohui Zhu^{a, b, e},
Meng Qin^{a, b, e},
Shuo Guan^{a, b, e},
Yixin Ren^{a, b, e},
Ying Kuo^{a, b, e},
Di Chang^{a, b, e},
Wei Chen^{a, b, c, d},
Peng Yuan^{a, b, e},
Liying Yan^{a, b, e},
Jie Qiao^{a, b, c, e, f}

a
Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing 100191, China
b
Key Laboratory of Assisted Reproduction, Ministry of Education, Beijing 100191, China
c
Peking-Tsinghua Center for Life Sciences, Peking University, Beijing 100871, China
d
Academy for Advanced Interdisciplinary Studies, Peking University, Beijing 100871, China
e
Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproduction, Beijing 100191, China
f
Beijing Advanced Innovation Center for Genomics (ICG), Peking University, Beijing 100871, China

More Information

Corresponding author: E-mail address: yanliyingkind@aliyun.com (Liying Yan); E-mail address: jie.qiao@263.net (Jie Qiao)
Received Date: 2018-01-25
Accepted Date: 2018-05-13
Rev Recd Date: 2018-03-28

Available Online: 2018-07-11

Publish Date: 2018-09-20

Abstract

FullText(HTML)

References(12)

References

[1]	Fiorentino, F., Spizzichino, L., Bono, S. et al. PGD for reciprocal and Robertsonian translocations using array comparative genomic hybridization Hum. Reprod., 26 (2011),pp. 1925-1935
[2]	Fischer, J., Colls, P., Escudero, T. et al. Preimplantation genetic diagnosis (PGD) improves pregnancy outcome for translocation carriers with a history of recurrent losses Fertil. Steril., 94 (2010),pp. 283-289
[3]	Hu, L., Cheng, D., Gong, F. et al. Reciprocal translocation carrier diagnosis in preimplantation human embryos EBioMedicine, 14 (2016),pp. 139-147
[4]	Li, G., Jin, H., Xin, Z. et al. Increased IVF pregnancy rates after microarray preimplantation genetic diagnosis due to parental translocations Syst. Biol. Reprod. Med., 60 (2014),pp. 119-124
[5]	Mackie, O.C., Scriven, P.N. Meiotic outcomes in reciprocal translocation carriers ascertained in 3-day human embryos Eur. J. Hum. Genet., 10 (2002),pp. 801-806
[6]	Scriven, P.N., Handyside, A.H., Ogilvie, C.M. Chromosome translocations: segregation modes and strategies for preimplantation genetic diagnosis Prenat. Diagn., 18 (1998),pp. 1437-1449
[7]	Treff, N.R., Thompson, K., Rafizadeh, M. et al. SNP array-based analyses of unbalanced embryos as a reference to distinguish between balanced translocation carrier and normal blastocysts J. Assist. Reprod. Genet., 33 (2016),pp. 1115-1119
[8]	van Uum, C.M., Stevens, S.J., Dreesen, J.C. et al. SNP array-based copy number and genotype analyses for preimplantation genetic diagnosis of human unbalanced translocations Eur. J. Hum. Genet., 20 (2012),pp. 938-944
[9]	Xu, J., Fang, R., Chen, L. et al. Proc. Natl. Acad. Sci. U. S. A., 113 (2016),pp. 11907-11912
[10]	Xu, J., Zhang, Z., Niu, W. et al. Mapping allele with resolved carrier status of Robertsonian and reciprocal translocation in human preimplantation embryos Proc. Natl. Acad. Sci. U. S. A., 114 (2017),pp. E8695-E8702
[11]	Yan, L., Huang, L., Xu, L. et al. Live births after simultaneous avoidance of monogenic diseases and chromosome abnormality by next-generation sequencing with linkage analyses Proc. Natl. Acad. Sci. U. S. A., 112 (2015),pp. 15964-15969
[12]	Zhang, W., Liu, Y., Wang, L. et al. Clinical application of next-generation sequencing in preimplantation genetic diagnosis cycles for Robertsonian and reciprocal translocations J. Assist. Reprod. Genet., 33 (2016),pp. 899-906