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Volume 44 Issue 12
Dec.  2017
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Article Contents

Mediator complex components are frequent targets for genetic alterations in various types of human cancer

doi: 10.1016/j.jgg.2017.08.006
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  • Corresponding author: E-mail address: denglb1937@163.com (Libin Deng); E-mail address: hshi@augusta.edu (Huidong Shi)
  • Received Date: 2017-04-18
  • Accepted Date: 2017-08-25
  • Rev Recd Date: 2017-07-26
  • Available Online: 2017-11-23
  • Publish Date: 2017-12-20
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  • [1]
    Allen, B.L., Taatjes, D.J. The Mediator complex: a central integrator of transcription Nat. Rev. Mol. Cell Biol., 16 (2015),pp. 155-166
    [2]
    Cani, A.K., Hovelson, D.H., McDaniel, A.S. et al. Mol. Cancer Res., 13 (2015),pp. 613-619
    [3]
    Cerami, E., Gao, J., Dogrusoz, U. et al. The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data Cancer Discov., 2 (2012),pp. 401-404
    [4]
    Chapuy, B., McKeown, M.R., Lin, C.Y. et al. Discovery and characterization of super-enhancer-associated dependencies in diffuse large B cell lymphoma Cancer Cell, 24 (2013),pp. 777-790
    [5]
    Chipumuro, E., Marco, E., Christensen, C.L. et al. CDK7 inhibition suppresses super-enhancer-linked oncogenic transcription in MYCN-driven cancer Cell, 159 (2014),pp. 1126-1139
    [6]
    Christensen, C.L., Kwiatkowski, N., Abraham, B.J. et al. Targeting transcriptional addictions in small cell lung cancer with a covalent CDK7 inhibitor Cancer Cell, 26 (2014),pp. 909-922
    [7]
    Clarke, P.A., Ortiz-Ruiz, M.-J., TePoele, R. et al. Assessing the mechanism and therapeutic potential of modulators of the human Mediator complex-associated protein kinases eLife, 5 (2016)
    [8]
    Dehainault, C., Garancher, A., Castera, L. et al. Hum. Mol. Genet., 23 (2014),pp. 5243-5250
    [9]
    Jiang, Y.Y., Lin, D.C., Mayakonda, A. et al. Targeting super-enhancer-associated oncogenes in oesophageal squamous cell carcinoma Gut, 66 (2017),pp. 1358-1368
    [10]
    Kampjarvi, K., Kim, N.H., Keskitalo, S. et al. Prostate, 76 (2016),pp. 22-31
    [11]
    Kampjarvi, K., Park, M.J., Mehine, M. et al. Mutations in Exon 1 highlight the role of MED12 in uterine leiomyomas Hum. Mutat., 35 (2014),pp. 1136-1141
    [12]
    Kandaswamy, R., Sava, G.P., Speedy, H.E. et al. Genetic predisposition to chronic lymphocytic leukemia is mediated by a BMF super-enhancer polymorphism Cell Rep., 16 (2016),pp. 2061-2067
    [13]
    Lim, W.K., Ong, C.K., Tan, J. et al. Nat. Genet., 46 (2014),pp. 877-880
    [14]
    Mansour, M.R., Abraham, B.J., Anders, L. et al. Oncogene regulation. An oncogenic super-enhancer formed through somatic mutation of a noncoding intergenic element Science, 346 (2014),pp. 1373-1377
    [15]
    Pelish, H.E., Liau, B.B., II, Nitulescu, Tangpeerachaikul, A. et al. Mediator kinase inhibition further activates super-enhancer-associated genes in AML Nature, 526 (2015),pp. 273-276
    [16]
    Pott, S., Lieb, J.D. What are super-enhancers? Nat. Genet., 47 (2015),pp. 8-12
    [17]
    Spaeth, J.M., Kim, N.H., Boyer, T.G. Mediator and human disease Semin. Cell Dev. Biol., 22 (2011),pp. 776-787
    [18]
    Turunen, M., Spaeth, J.M., Keskitalo, S. et al. Cell Rep., 7 (2014),pp. 654-660
    [19]
    Yin, J.-W., Wang, G. The Mediator complex: a master coordinator of transcription and cell lineage development Development, 141 (2014),pp. 977-987
    [20]
    Zhang, Z., Peng, H., Wang, X. et al. Preclinical efficacy and molecular mechanism of targeting CDK7-dependent transcriptional addiction in ovarian cancer Mol. Cancer Ther., 16 (2017),pp. 1739-1750
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