FERM domain phosphorylation and endogenous 3′UTR are not essential for regulating the function and subcellular localization of polarity protein Crumbs

Haowei Cao; Rui Xu; Qiping Shi; Dandan Zhang; Juan Huang; Yang Hong

doi:10.1016/j.jgg.2017.08.002

Volume 44 Issue 8

Aug. 2017

Turn off MathJax

Article Contents

Article Navigation > Journal of Genetics and Genomics > 2017 > 44(8): 409-412

PDF( 1399 KB)

FERM domain phosphorylation and endogenous 3′UTR are not essential for regulating the function and subcellular localization of polarity protein Crumbs

doi: 10.1016/j.jgg.2017.08.002

a
Department of Biotechnology, School of Basic Medical Sciences, Nanjing Medical University, Nanjing 211166, China
b
Department of Cell Biology, University of Pittsburgh Medical School, Pittsburgh, PA 15261, USA

More Information

Corresponding author: E-mail address: huangjuan@njmu.edu.cn (Juan Huang); E-mail address: yang.hong@gmail.com (Yang Hong)
Received Date: 2017-06-19
Accepted Date: 2017-08-08
Rev Recd Date: 2017-08-02

Available Online: 2017-08-12

Publish Date: 2017-08-20

Abstract

FullText(HTML)

References(17)

References

[1]	Bachmann, A., Schneider, M., Theilenberg, E. et al. Nature, 414 (2001),pp. 638-643
[2]	Bilder, D., Schober, M., Perrimon, N. Integrated activity of PDZ protein complexes regulates epithelial polarity Nat. Cell Biol., 5 (2003),pp. 53-58
[3]	Fletcher, G.C., Lucas, E.P., Brain, R. et al. Curr. Biol., 22 (2012),pp. 1116-1122
[4]	Flores-Benitez, D., Knust, E. eLife, 4 (2015),p. e07398
[5]	Hong, Y., Stronach, B., Perrimon, N. et al. Nature, 414 (2001),pp. 634-638
[6]	Huang, J., Zhou, W., Dong, W. et al. Proc. Natl. Acad. Sci. U. S. A., 106 (2009),pp. 8284-8289
[7]	Klebes, A., Knust, E. Curr. Biol., 10 (2000),pp. 76-85
[8]	Lemmers, C., Michel, D., Lane-Guermonprez, L. et al. CRB3 binds directly to Par6 and regulates the morphogenesis of the tight junctions in mammalian epithelial cells Mol. Biol. Cell, 15 (2004),pp. 1324-1333
[9]	Li, Z., Wang, L., Hays, T.S. et al. Dynein-mediated apical localization of crumbs transcripts is required for Crumbs activity in epithelial polarity J. Cell Biol., 180 (2008),pp. 31-38
[10]	Medina, E., Williams, J., Klipfell, E. et al. J. Cell Biol., 158 (2002),pp. 941-951
[11]	Roh, M.H., Makarova, O., Liu, C.J. et al. The Maguk protein, Pals1, functions as an adapter, linking mammalian homologues of Crumbs and Discs Lost J. Cell Biol., 157 (2002),pp. 161-172
[12]	Sotillos, S., Diaz-Meco, M.T., Caminero, E. et al. J. Cell Biol., 166 (2004),pp. 549-557
[13]	Tanentzapf, G., Tepass, U. Interactions between the crumbs, lethal giant larvae and bazooka pathways in epithelial polarization Nat. Cell Biol., 5 (2003),pp. 46-52
[14]	Tepass, U., Knust, E. Dev. Biol., 159 (1993),pp. 311-326
[15]	Tepass, U., Theres, C., Knust, E. Cell, 61 (1990),pp. 787-799
[16]	Wei, Z., Li, Y., Ye, F. et al. Structural basis for the phosphorylation-regulated interaction between the cytoplasmic tail of cell polarity protein crumbs and the actin-binding protein moesin J. Biol. Chem., 290 (2015),pp. 11384-11392
[17]	Wodarz, A., Hinz, U., Engelbert, M. et al. Cell, 82 (1995),pp. 67-76