Efficient generation of the mouse model with a defined point mutation through haploid cell-mediated gene editing

Leixin Wei; Xiukun Wang; Suming Yang; Wen Yuan; Jinsong Li

doi:10.1016/j.jgg.2017.07.004

Volume 44 Issue 9

Sep. 2017

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Article Navigation > Journal of Genetics and Genomics > 2017 > 44(9): 461-463

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Efficient generation of the mouse model with a defined point mutation through haploid cell-mediated gene editing

doi: 10.1016/j.jgg.2017.07.004

Leixin Wei^{1, 2, #},
Xiukun Wang^{3, #},
Suming Yang³,
Wen Yuan⁴,
Jinsong Li⁵

1
Department of Orthopaedic Surgery, Changzheng Hospital, The Second Military Medical University, Shanghai 200003, China
2
State Key Laboratory of Cell Biology, Shanghai Key Laboratory of Molecular Andrology, CAS Center for Excellence in Molecular Cell Science, Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences; University of Chinese Academy of Sciences, Shanghai 200031, China
3
State Key Laboratory of Cell Biology, Shanghai Key Laboratory of Molecular Andrology, CAS Center for Excellence in Molecular Cell Science, Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences; University of Chinese Academy of Sciences, Shanghai 200031, China
4
Department of Orthopaedic Surgery, Changzheng Hospital, The Second Military Medical University, Shanghai 200003, China
5
State Key Laboratory of Cell Biology, Shanghai Key Laboratory of Molecular Andrology, CAS Center for Excellence in Molecular Cell Science, Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences; University of Chinese Academy of Sciences, Shanghai 200031, China

More Information

Corresponding author: E-mail address: yuanwenspine@163.com (Wen Yuan); E-mail address: jsli@sibcb.ac.cn (Jinsong Li)
Received Date: 2017-06-02
Accepted Date: 2017-07-18
Rev Recd Date: 2017-07-13

Available Online: 2017-08-12

Publish Date: 2017-09-20

Abstract

These authors contributed equally to this work.

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References(10)

References

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