Large-scale genome-wide scans do not support petaloid toenail as a Mendelian trait

Manfei Zhang; Sijie Wu; Juan Zhang; Yajun Yang; Jingze Tan; Haijuan Guan; Yu Liu; Kun Tang; Jean Krutmann; Shuhua Xu; Li Jin; Yaqun Guan; Hui Li; Sijia Wang

doi:10.1016/j.jgg.2016.10.003

Volume 43 Issue 12

Dec. 2016

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Article Navigation > Journal of Genetics and Genomics > 2016 > 43(12): 702-704

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Large-scale genome-wide scans do not support petaloid toenail as a Mendelian trait

doi: 10.1016/j.jgg.2016.10.003

Manfei Zhang^{1, 2, #},
Sijie Wu^{3, 4, #},
Juan Zhang^{5, 6, #},
Yajun Yang^{5, 6, #},
Jingze Tan⁷,
Haijuan Guan⁷,
Yu Liu^{8, 9},
Kun Tang^{8, 9},
Jean Krutmann¹⁰,
Shuhua Xu^{11, 12, 13},
Li Jin^{14, 15, 16},
Yaqun Guan¹⁷,
Hui Li¹⁸,
Sijia Wang¹⁹

1
Ministry of Education Key Laboratory of Contemporary Anthropology, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai 200438, China
2
Chinese Academy of Sciences Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China
3
Chinese Academy of Sciences Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China
4
University of Chinese Academy of Sciences, Beijing 100049, China
5
Ministry of Education Key Laboratory of Contemporary Anthropology, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai 200438, China
6
Fudan-Taizhou Institute of Health Sciences, Taizhou 225300, China
7
Ministry of Education Key Laboratory of Contemporary Anthropology, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai 200438, China
8
Chinese Academy of Sciences Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China
9
University of Chinese Academy of Sciences, Beijing 100049, China
10
IUF-Leibniz Research Institute for Environmental Medicine, Düsseldorf 40225, Germany
11
Chinese Academy of Sciences Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China
12
University of Chinese Academy of Sciences, Beijing 100049, China
13
School of Life Science and Technology, Shanghai Tech University, Shanghai 200031, China
14
Ministry of Education Key Laboratory of Contemporary Anthropology, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai 200438, China
15
Chinese Academy of Sciences Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China
16
Fudan-Taizhou Institute of Health Sciences, Taizhou 225300, China
17
Department of Biochemistry and Molecular Biology, Preclinical Medicine College, Xinjiang Medical University, Urumqi 830011, China
18
Ministry of Education Key Laboratory of Contemporary Anthropology, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai 200438, China
19
Chinese Academy of Sciences Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China

More Information

Corresponding author: E-mail address: yaqunguan@163.com (Yaqun Guan); E-mail address: LHCA@fudan.edu.cn (Hui Li); E-mail address: wangsijia@picb.ac.cn (Sijia Wang)
Received Date: 2016-07-08
Accepted Date: 2016-10-12
Rev Recd Date: 2016-09-28

Available Online: 2016-10-14

Publish Date: 2016-12-20

Abstract

These authors contributed equally to this study.

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References(5)

References

[1]	Chi, C.C., Wang, S.H. Inherited accessory nail of the fifth toe cured by surgical matricectomy Dermatol. Surg., 30 (2004),pp. 1177-1179
[2]	Gao, J.
[3]	Hao, W., Bian, J., Zhu, P. Petaloid toenails: its types, distribution and hereditary mode-a survey of a village in Zhouzhi county, Shaanxi Province, China Acta Anthropol. Sin., 24 (2005),pp. 319-327
[4]	Xu, S., Jin, L. A genome-wide analysis of admixture in Uyghurs and a high-density admixture map for disease-gene discovery Am. J. Hum. Genet., 83 (2008),pp. 322-336
[5]	Yang, J.A., Lee, S.H., Goddard, M.E. et al. GCTA: a tool for genome-wide complex trait analysis Am. J. Hum. Genet., 88 (2011),pp. 76-82