Genetic Polymorphism of Mitochondrial DNA in Dong, Gelao, Tujia, and Yi Ethnic Populations from Guizhou, China

Binbin Li; Fuguang Zhong; Hongsheng Yi; Xianran Wang; Liangfang Li; Lilan Wang; Xiaolan Qi; Lifu Wu

doi:10.1016/S1673-8527(07)60091-5

Volume 34 Issue 9

Sep. 2007

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Genetic Polymorphism of Mitochondrial DNA in Dong, Gelao, Tujia, and Yi Ethnic Populations from Guizhou, China

doi: 10.1016/S1673-8527(07)60091-5

a
Department of Pathophysiology, Guangdong Medical College, Zhanjiang 524023, China
b
Institute of Medicine Science, Guiyang Medical College, Guiyang 550004, China
c
The People's Hospital of Tianzhu County, Tianzhu 556700, China
d
The People's Hospital of Hezhang County, Hezhang 553200, China
e
The People's Hospital of Wuchuan County, Wuchuan 564300, China

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Corresponding author: E-mail address: zhongfuguang@hotmail.com (Fuguang Zhong)
Received Date: 2006-08-21
Accepted Date: 2007-03-11

Available Online: 2007-09-18

Publish Date: 2007-09-20

Abstract

Abstract

To reveal the genetic structures and relationships of the four ethnic populations from the maternal inheritance and explore the origins and migrations of nationalities, the genetic polymorphism of mtDNA in Dong, Gelao, Tujia, and Yi populations from Guizhou was studied by direct sequencing of hypervariable segment I(HVS I) and PCR-RFLP of coding region. Thirty-seven (sub-) haplogroups were identified in the classification tree of mtDNA haplogroups. Haplogroup distributions and principal component (PC) analysis showed that the Dong has high frequencies of south-prevalent haplogroups, which indicates that it is a typically southern population. The Yi harbors high frequencies of the south-prevalent and northern-prevalent haplogroups, which demonstrates that it inherits the maternal characteristics from both southern and northern populations. The Yi and Gelao cluster together, the reason for which might be that their ancestries frequently underwent gene exchanges and mixtures.
- ethnic populations in Guizhou,
- mitochondrial DNA,
- polymorphism

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References

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